Spectral profile
2 methods · 2004–2009
Spectral profile: Each spectrum summarised as a probability profile over residues or fragment positions, from which the sequence is read as the most likely path rather than by matching peaks one at a time.
Each spectrum summarised as a probability profile over residues or fragment positions, from which the sequence is read as the most likely path rather than by matching peaks one at a time.
The earliest of its 2 methods is Probability profile method (ORNL) (2004).
| Methods | 2 |
| Papers describing them | 3 |
| Authors | 12 |
| Active | 2004-03-30 to 2009-06-01 |
| Kinds | algorithm (2) |
| Acquisition | DDA (2) |
Methods (2)
Oldest first, by the paper that describes each one.
- Probability profile method (ORNL) (2004): Learns neighbourhood patterns of b, y and related peaks from resolved spectra to assign each peak a category probability, giving anchor points for de novo sequence assembly.
- MS-Profile (2009): Spectral profile representation for gapped de novo peptide sequencing and identification.
Papers describing them (3)
- Probability profiles-novel approach in tandem mass spectrometry De Novo sequencing (2004, Computational Systems Bioinformatics. CSB2003. Proceedings of the 2003 IEEE Bioinformatics Conference. CSB2003, peer-reviewed)
- Probability profile method - new approach to data analysis in tandem mass spectrometry (2004, Proceedings. 2004 IEEE Computational Systems Bioinformatics Conference, 2004. CSB 2004, peer-reviewed)
- Spectral Profiles, a Novel Representation of Tandem Mass Spectra and Their Applications for de Novo Peptide Sequencing and Identification (2009, Molecular & Cellular Proteomics, peer-reviewed)