Abstract 4402 De Novo Peptidomics and Bioprospecting Reveal Antimicrobial Peptide Candidates in Cryptobranchus alleganiensis (Hellbender) Skin Secretions
abstract · Journal of Biological Chemistry · 2026
abstract · Journal of Biological Chemistry · 2026. Syeda Raika Shahid et al.
| Date | 2026-05-01 |
| Type | abstract |
| Venue | Journal of Biological Chemistry |
| Publisher | American Society for Biochemistry and Molecular Biology |
| Contribution | downstream-application |
| DOI | 10.1016/j.jbc.2026.112633 |
| Venue 2-year citedness | 1.83 |
Methods and tools
- Hellbender skin AMPs: Bioprospects the skin secretions of Cryptobranchus alleganiensis, the hellbender salamander, for antimicrobial peptide candidates. Solid-phase extraction enrichment and Orbitrap Fusion acquisition, PEAKS de novo sequencing of the secretion peptides, then antimicrobial prediction over the de novo sequences. The third GMU host-defence peptide record in the catalog, alongside the red-legged salamander and hemp seed abstracts from the same lab.