Venomics and antivenomics of Indian spectacled cobra (Naja naja) from the Western Ghats
peer-reviewed · Acta Tropica · 2022
peer-reviewed · Acta Tropica · 2022. Muralidharan Vanuopadath et al.
| Date | 2022-01-28 |
| Type | peer-reviewed |
| Venue | Acta Tropica |
| Publisher | Elsevier |
| Contribution | downstream-application |
| DOI | 10.1016/j.actatropica.2022.106324 |
| Citations (OpenAlex) | 19 |
Methods and tools
- Naja naja venomics: Venomics + antivenomics workflow using SDS-PAGE, RP-HPLC and Q-TOF LC-MS/MS with PEAKS + Novor de novo sequencing to identify 115 proteins across 17 venom protein families in Indian cobra venom from the Western Ghats, and benchmark polyvalent-antivenom recognition.
- Novor: Real-time decision-tree scoring
- PEAKS: Commercial DP-based de novo
Cites (4)
- Delineating the venom toxin arsenal of Malabar pit viper (Trimeresurus malabaricus) from the Western Ghats of India and evaluating its immunological cross-reactivity and in vitro cytotoxicity (2020) crossref
- Mass spectrometry-assisted venom profiling of Hypnale hypnale found in the Western Ghats of India incorporating de novo sequencing approaches (2018) crossref
- A Review and Database of Snake Venom Proteomes (2017) crossref
- DeNovoGUI: An Open Source Graphical User Interface for de Novo Sequencing of Tandem Mass Spectra (2014) crossref