InstaNovo+

algorithm · Diffusion

InstaNovo+: algorithm · Diffusion. Multinomial diffusion

Multinomial diffusion

Kind	algorithm
Family	Diffusion
Deep learning	yes
Acquisition	DDA

Code

• https://github.com/instadeepai/instanovo

Live stars, open issues and last-push figures are on the Code activity chart.

Papers

• Lactation-stage specific protein shifts in koala milk mirror the joey’s growth needs (2026, International Journal of Biological Macromolecules, peer-reviewed)
• Characterisation of pouch secretions from breeding Tasmanian devils (2026, Reproduction, peer-reviewed)
• InstaNovo enables diffusion-powered de novo peptide sequencing in large-scale proteomics experiments (2025, Nature Machine Intelligence, peer-reviewed)
• De novo peptide sequencing with InstaNovo: Accurate, database-free peptide identification for large scale proteomics experiments (2023, bioRxiv, preprint)

Authors (28)

Kevin Eloff, Konstantinos Kalogeropoulos, Oliver Morell, Amandla Mabona, Jakob Berg Jespersen, Wesley Williams, Sam P. B. van Beljouw, Marcin J. Skwark, Andreas Hougaard Laustsen, Stan J. J. Brouns, Anne Ljungars, Erwin M. Schoof, Jeroen Van Goey, Ulrich auf dem Keller, Karim Beguir, Nicolas Lopez Carranza, Timothy P. Jenkins, Rachel Catzel, Esperanza Rivera-de-Torre, Manujaya W. Jayamanna Mohottige, Emma Peel, Angéla Juhász, Mitchell G. Nye-Wood, Katherine Belov, Michelle L. Colgrave, Carolyn J. Hogg, Katherine A. Farquharson, Tawfeek Khedr

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