Multiplex De Novo Sequencing of Peptide Antibiotics

peer-reviewed · Lecture Notes in Computer Science · 2011

peer-reviewed · Lecture Notes in Computer Science · 2011. Hosein Mohimani et al.
Date 2011-03-23
Type peer-reviewed
Venue Lecture Notes in Computer Science
Publisher Springer Berlin Heidelberg
Contribution algorithm
DOI 10.1007/978-3-642-20036-6_24
Citations (OpenAlex) 3
Venue 2-year citedness 1.54

Authors

  1. Hosein Mohimani · Carnegie Mellon University, University of California San Diego
  2. Wei-Ting Liu · University of California San Diego
  3. Yu-Liang Yang · University of California San Diego
  4. Susana P. Gaudêncio · Scripps Institution of Oceanography, University of California San Diego
  5. William Fenical · Scripps Institution of Oceanography, University of California San Diego
  6. Pieter C. Dorrestein · Scripps Institution of Oceanography, University of California San Diego, University of California System
  7. Pavel A. Pevzner · Max Planck Institute of Molecular Cell Biology and Genetics, Saint Petersburg Academic University, St Petersburg University, St. Petersburg State University, University of California San Diego, University of Southern California

Methods and tools

  • NRP dereplication and sequencing: Sequences cyclic nonribosomal peptides from multistage mass spectrometry by spectral alignment, and dereplicates them comparatively against known NRPs. The first high-throughput route to a compound class with no genome to search and considerable pharmacological interest.

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